Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRPK1 | Q96SB4 | 2/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.54 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | WDR5 | P61964 | 4/20 | 0.53 |
| ▸ | XPO1 | O14980 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29204844 | 0.87 | RXFP1 (0.56) | WDR5XPO1KMT2AMAPTALDH1A1 | |
| SCHEMBL29204813 | 0.87 | WDR5 (0.57) | WDR5XPO1KMT2AMAPTALDH1A1 | |
| SCHEMBL29204824 | 0.82 | XPO1 (0.61) | SRPK1KDRSRPK2SRPK3TP53 | |
| SCHEMBL13659894 | 0.82 | MAPT (0.62) | SRPK1KDRSRPK2SRPK3TP53 | |
| SCHEMBL1481753 | 0.80 | DDR1 (0.52) | TP53MAPTALDH1A1 | |
| SCHEMBL29204841 | 0.80 | XPO1 (0.66) | TP53WDR5XPO1KMT2AMAPT | |
| SCHEMBL17305365 | 0.79 | ERAP1 (0.48) | KMT2AMAPTMEN1TSHRGAA | |
| SCHEMBL29204837 | 0.79 | XPO1 (0.65) | SRPK1KDRSRPK2SRPK3TP53 | |
| SCHEMBL29204820 | 0.78 | XPO1 (0.67) | SRPK1KDRSRPK2SRPK3TP53 | |
| SCHEMBL7662821 | 0.77 | NPC1 (0.53) | WDR5KMT2AMAPTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964578-A | Non-covalent CRM1 inhibitor and preparation method and application thereof | 四川大学 | 2024-05-03 | — | — | CN | disclosed |