Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30828288 | 1.00 | NPC1 (0.46) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL29205127 | 0.86 | ALOX5 (0.42) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL29205157 | 0.85 | ALOX5 (0.44) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL27166105 | 0.84 | GAA (0.46) | NPC1RAB9AMEN1KMT2AHPGD | |
| SCHEMBL27166148 | 0.83 | HSP90AA1 (0.39) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL29205140 | 0.82 | MAPK13 (0.38) | HPGDALDH1A1SMN1; SMN2AKR1C3 | |
| SCHEMBL27166172 | 0.82 | AKR1C3 (0.53) | MEN1KMT2ASMN1; SMN2AKR1C3 | |
| SCHEMBL29205169 | 0.82 | HPGD (0.38) | HPGDALDH1A1AKR1C3 | |
| SCHEMBL27166076 | 0.81 | HSD11B1 (0.43) | MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL27166039 | 0.81 | NAMPT (0.51) | HPGDKCNH2NAMPTAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794899-A | Novel heterocyclic compounds, compositions, methods of preparation and uses thereof | 欧加农研发芬兰有限公司 | 2024-03-29 | — | — | CN | disclosed |