Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.70 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.70 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.70 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.68 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.60 |
| ▸ | GAK | O14976 | 2/20 | 0.60 |
| ▸ | COQ8A | Q8NI60 | 2/20 | 0.60 |
| ▸ | NLK | Q9UBE8 | 2/20 | 0.60 |
| ▸ | KDR | P35968 | 4/20 | 0.50 |
| ▸ | CLK2 | P49760 | 3/20 | 0.50 |
| ▸ | HIPK4 | Q8NE63 | 3/20 | 0.50 |
| ▸ | SRPK1 | Q96SB4 | 3/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.50 |
| ▸ | STK17A | Q9UEE5 | 3/20 | 0.50 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.50 |
| ▸ | ROS1 | P08922 | 2/20 | 0.50 |
| ▸ | CDK2 | P24941 | 2/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3064565 | 0.87 | HTR1A (0.67) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL31673817 | 0.85 | HTR1A (0.72) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL25466634 | 0.79 | GAK (0.70) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL29205284 | 0.79 | EGFR (0.64) | RIPK2GAKCOQ8ANLKACVR1 | |
| SCHEMBL2205672 | 0.79 | GAK (0.65) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL3841526 | 0.78 | HTR1A (0.58) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL16596283 | 0.78 | HTR1A (0.84) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL19633676 | 0.78 | GAK (0.68) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL8145365 | 0.78 | HTR1A (0.61) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL25466706 | 0.77 | GAK (0.67) | HTR1AADRA1DADRA1AADRA1BFERMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999075-A | Compounds and pharmaceutical compositions comprising inhibitors of amyloid peptide interaction with glycosaminoglycans, methods of treatment, and uses thereof | 吉斯莫治疗股份有限公司 | 2024-05-07 | — | — | CN | disclosed |