Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.64 |
| ▸ | SRC | P12931 | 3/20 | 0.62 |
| ▸ | GAK | O14976 | 3/20 | 0.62 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.62 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.62 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.62 |
| ▸ | ABL1 | P00519 | 1/20 | 0.62 |
| ▸ | LCK | P06239 | 1/20 | 0.62 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.62 |
| ▸ | EPHA8 | P29322 | 1/20 | 0.62 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.62 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.62 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.62 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.62 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.52 |
| ▸ | KRAS | P01116 | 2/20 | 0.52 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.49 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15607569 | 0.85 | EGFR (0.66) | EGFRSRCGAKBMPR1BEPHB6 | |
| SCHEMBL4400367 | 0.80 | PDGFRB (0.72) | EGFRSRCPDGFRAPDGFRBFGFR2 | |
| SCHEMBL14966516 | 0.79 | EGFR (0.75) | EGFRSRCGAKBMPR1BEPHB6 | |
| SCHEMBL3064565 | 0.79 | HTR1A (0.67) | GAKRIPK2COQ8ANLK | |
| SCHEMBL29205334 | 0.79 | HTR1A (0.70) | EGFRGAKRIPK2ACVR1COQ8A | |
| SCHEMBL21358588 | 0.78 | PDGFRA (0.60) | EGFRSRCGAKBMPR1BEPHB6 | |
| SCHEMBL22455222 | 0.78 | EGFR (0.58) | EGFRSRCGAKBMPR1BEPHB6 | |
| SCHEMBL8501712 | 0.78 | EGFR (0.74) | EGFRSRCGAKBMPR1BEPHB6 | |
| Amiquinsin SCHEMBL242841 | 0.77 | EHMT2 (0.63) | EGFRSRCGAKBMPR1BEPHB6 | |
| SCHEMBL30880708 | 0.77 | GAK (0.75) | EGFRSRCGAKBMPR1BEPHB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999075-A | Compounds and pharmaceutical compositions comprising inhibitors of amyloid peptide interaction with glycosaminoglycans, methods of treatment, and uses thereof | 吉斯莫治疗股份有限公司 | 2024-05-07 | — | — | CN | disclosed |