Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | GLI1 | P08151 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16112345 | 0.71 | KDM4E (0.34) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL29585508 | 0.67 | KMT2A (0.38) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL238946 | 0.66 | — | — | |
| SCHEMBL8596049 | 0.66 | — | — | |
| SCHEMBL938236 | 0.66 | — | — | |
| SCHEMBL4198280 | 0.65 | — | — | |
| SCHEMBL1363759 | 0.65 | GAA (0.32) | KMT2A | |
| SCHEMBL13225971 | 0.65 | GAA (0.32) | KMT2A | |
| SCHEMBL13225975 | 0.65 | GAA (0.32) | KMT2A | |
| SCHEMBL27671928 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715658-A | Method for inhibiting RAS | 锐新医药公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-117616031-A | RAS inhibitors for the treatment of cancer | 锐新医药公司 | 2024-02-27 | — | — | CN | disclosed |