⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8596049 | 1.00 | — | — | |
| SCHEMBL238946 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL27830317 | 0.97 | — | — | |
| SCHEMBL9021240 | 0.90 | APLNR (0.41) | — | |
| Bicarbonate SCHEMBL9021243 | 0.88 | APLNR (0.39) | — | |
| SCHEMBL13592131 | 0.83 | APLNR (0.34) | — | |
| SCHEMBL27642392 | 0.82 | CHRNB2 (0.31) | — | |
| SCHEMBL11517493 | 0.78 | CHRNB2 (0.36) | — | |
| SCHEMBL16431076 | 0.76 | PKM (0.36) | — | |
| SCHEMBL4198280 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 325 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117942620-A | Method and system for efficiently separating carbon dioxide phase-change solution | 中国石油化工股份有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-117618988-A | Separation method and separation device for carbon dioxide-containing phase-change solution | 中国石油化工股份有限公司 | 2024-03-01 | — | — | CN | claimed |
| WO-2024031901-A1 | SEPARATION METHOD AND SEPARATION APPARATUS FOR CARBON-DIOXIDE-CONTAINING PHASE CHANGE SOLUTION | 中国石油化工股份有限公司 | 2024-02-15 | — | — | WO | claimed |
| CN-114196659-B | Amidase mutant, coding gene, engineering bacteria and application thereof | 浙江工业大学 | 2024-02-13 | — | — | CN | claimed |
| CN-115108934-B | Preparation method of cilastatin intermediate sodium | 珠海联邦制药股份有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-117279906-A | Substituted heterocyclic compounds | 百时美施贵宝公司 | 2023-12-22 | — | — | CN | claimed |
| CN-115108934-A | Preparation method of cilastatin intermediate sodium | 珠海联邦制药股份有限公司 | 2022-09-27 | — | — | CN | claimed |
| CN-114196659-A | Amidase mutant, coding gene, engineering bacterium and application thereof | 浙江工业大学 | 2022-03-18 | — | — | CN | claimed |
| CN-110265608-B | Nano coating diaphragm for high-voltage-resistant lithium ion battery and preparation method thereof | 新乡市中科科技有限公司 | 2021-10-01 | — | — | CN | claimed |
| CN-110265608-A | A kind of high pressure resistant lithium ion battery nano coating diaphragm and preparation method thereof | 新乡市中科科技有限公司 | 2019-09-20 | — | — | CN | claimed |
| CN-1562962-A | Method ofr synthesizing S-(1)-2.2 dimethylcyclopropane formamide | UNIV ZHEJIANG (CN) | 2005-01-12 | — | — | CN | claimed |
| EP-0524604-B1 | Process for the preparations of S-(+)-2,2-dimethyl-cyclopropane carboxamid by genetically engineered microorganismes | LONZA AG (CH) | 1998-10-14 | — | — | EP | claimed |
| EP-0502525-B1 | Biotechnological process for the production of S-(+)-2,2-dimethylcyclopropanecarboxamide and R-(-)-2,2-dimethylcyclopropanecarboxylic acid | LONZA AG (CH) | 1996-06-26 | — | — | EP | claimed |
| US-5427934-A | A new DNA isolation from microorganism that codes for a stereospecific hydrolase, ligation of DNA in expression vector results hybrid plasmid, which is transformed in microorganism, which biotransform amide to acid and isomer of amide | LONZA LTD. (CH) | 1995-06-27 | — | — | US | claimed |
| US-5360731-A | Bacteria capable of stereospecifically hydrolyzing R-(-)-2,2-dimethylcyclopropanecarboxamide | LONZA LTD. (CH) | 1994-11-01 | — | — | US | claimed |
| US-5273903-A | Biotransforming the R(-) isomer in a racemic mixture with Comamonas or an enzyme from this microorganism | LONZA LTD. (CH) | 1993-12-28 | — | — | US | claimed |
| EP-0524604-A2 | Process for the preparations of S-(+)-2,2-dimethyl-cyclopropane carboxamid by genetically engineered microorganismes | LONZA A.G. (CH) | 1993-01-27 | — | — | EP | claimed |
| EP-0502525-A1 | Biotechnological process for the production of S-(+)-2,2-dimethylcyclopropanecarboxamide and R-(-)-2,2-dimethylcyclopropanecarboxylic acid | LONZA AG (CH) | 1992-09-09 | — | — | EP | claimed |
| EP-0155779-B1 | A METHOD FOR THE OPTICAL PURIFICATION OF AN OPTICALLY ACTIVE 2,2-DIMETHYLCYCLOPROPANECARBOXYLIC ACID AMIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-04-26 | — | — | EP | claimed |
| EP-0155779-A1 | A method for the optical purification of an optically active 2,2-dimethylcyclopropanecarboxylic acid amide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-09-25 | — | — | EP | claimed |