Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | NQO2 | P16083 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13609766 | 0.87 | KCNA3 (0.52) | KCNA3KDM4ENQO2ALDH1A1SMN1; SMN2 | |
| SCHEMBL11540274 | 0.81 | NPSR1 (0.47) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL30783436 | 0.80 | KCNA3 (0.61) | KCNA3KDM4ENQO2ALDH1A1SMN1; SMN2 | |
| SCHEMBL11379787 | 0.80 | KCNA3 (0.61) | KCNA3KDM4ENQO2ALDH1A1SMN1; SMN2 | |
| SCHEMBL24522892 | 0.78 | KCNA3 (0.70) | KCNA3ALDH1A1SMN1; SMN2HPGDBRD4 | |
| SCHEMBL11541711 | 0.77 | MAPT (0.47) | ALDH1A1BRD4HSD17B10TSHR | |
| SCHEMBL22530365 | 0.77 | KDM4E (0.47) | KDM4EALDH1A1HPGDBRD4TSHR | |
| SCHEMBL11541055 | 0.76 | NPSR1 (0.46) | KDM4EALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL11540070 | 0.76 | NPSR1 (0.46) | KDM4EALDH1A1SMN1; SMN2HPGDBRD4 | |
| SCHEMBL11540561 | 0.76 | TSHR (0.45) | ALDH1A1SMN1; SMN2HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946000-A | Synthesis method of 1-methyl-2-oxo-1, 2-dihydro-4-quinolinecarboxylic acid methyl ester | 南通大学 | 2024-04-30 | — | — | CN | claimed |
| CN-117946000-A | Synthesis method of 1-methyl-2-oxo-1, 2-dihydro-4-quinolinecarboxylic acid methyl ester | 南通大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-117946000-A | Synthesis method of 1-methyl-2-oxo-1, 2-dihydro-4-quinolinecarboxylic acid methyl ester | 南通大学 | 2024-04-30 | — | — | CN | disclosed |