Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | APLNR | P35414 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11541711 | 0.86 | MAPT (0.47) | TSHRALDH1A1RECQLHSD17B10HTT | |
| SCHEMBL11543010 | 0.85 | HTT (0.42) | TSHRAPLNRALDH1A1RECQLHSD17B10 | |
| SCHEMBL11542874 | 0.85 | PTPN1 (0.42) | TSHRMEN1KMT2AAPLNRALDH1A1 | |
| SCHEMBL11541058 | 0.81 | ALDH1A1 (0.42) | APLNRALDH1A1RECQLHSD17B10HTT | |
| SCHEMBL11540274 | 0.81 | NPSR1 (0.47) | TSHRKMT2AATMALDH1A1RECQL | |
| SCHEMBL11538165 | 0.81 | NPSR1 (0.51) | MEN1KMT2AHTT | |
| SCHEMBL11540447 | 0.80 | POLB (0.45) | MEN1KMT2AALDH1A1HTTGAA | |
| SCHEMBL11542615 | 0.80 | NPSR1 (0.46) | MEN1KMT2AHTT | |
| SCHEMBL11540070 | 0.77 | NPSR1 (0.46) | TSHRKMT2AALDH1A1HSD17B10HTT | |
| SCHEMBL11541055 | 0.77 | NPSR1 (0.46) | MEN1KMT2AALDH1A1HSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168312-A | Quinolone derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-09-18 | — | — | US | claimed |