Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.55 |
| ▸ | NR3C2 | P08235 | 13/20 | 0.55 |
| ▸ | PGR | P06401 | 11/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL292065 | 0.79 | NR3C1 (0.48) | NR3C1NR3C2PGR | |
| SCHEMBL452414 | 0.78 | NR3C1 (0.85) | NR3C1NR3C2PGR | |
| SCHEMBL4474045 | 0.74 | NR3C1 (0.80) | NR3C1NR3C2PGR | |
| SCHEMBL292090 | 0.73 | NR3C1 (0.79) | NR3C1NR3C2PGR | |
| SCHEMBL292067 | 0.73 | NR3C1 (0.43) | NR3C1NR3C2PGR | |
| SCHEMBL27778243 | 0.71 | NR3C1 (0.57) | NR3C1NR3C2PGR | |
| SCHEMBL4466748 | 0.71 | NR3C1 (1.00) | NR3C1NR3C2PGR | |
| SCHEMBL291954 | 0.70 | NR3C1 (0.85) | NR3C1NR3C2PGR | |
| SCHEMBL291233 | 0.70 | NR3C1 (0.86) | NR3C1NR3C2PGR | |
| SCHEMBL292478 | 0.69 | NR3C1 (1.00) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049112-B1 | TREATING INFECTIONS AND SEQUELAE THEREOF WITH COMBINED DISSOCIATED GLUCOCORTICOID RECEPTOR AGONISTS AND ANTI-INFECTIVE AGENTS | BAUSCH & LOMB (US) | 2012-03-14 | — | — | EP | disclosed |