Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 11/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 9/20 | 0.43 |
| ▸ | PGR | P06401 | 9/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL292065 | 0.77 | NR3C1 (0.48) | NR3C1NR3C2PGR | |
| SCHEMBL292066 | 0.73 | NR3C1 (0.55) | NR3C1NR3C2PGR | |
| SCHEMBL452414 | 0.65 | NR3C1 (0.85) | NR3C1NR3C2PGR | |
| SCHEMBL18885180 | 0.62 | RORC (0.58) | — | |
| SCHEMBL30921781 | 0.62 | PTGDR2 (0.40) | NR3C2CYP2C9 | |
| SCHEMBL4474045 | 0.61 | NR3C1 (0.80) | NR3C1NR3C2PGR | |
| SCHEMBL292090 | 0.61 | NR3C1 (0.79) | NR3C1NR3C2PGR | |
| SCHEMBL1680297 | 0.61 | NR3C1 (0.48) | NR3C1NR3C2PGRAR | |
| SCHEMBL15991500 | 0.60 | SRC (0.37) | CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4466748 | 0.60 | NR3C1 (1.00) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049112-B1 | TREATING INFECTIONS AND SEQUELAE THEREOF WITH COMBINED DISSOCIATED GLUCOCORTICOID RECEPTOR AGONISTS AND ANTI-INFECTIVE AGENTS | BAUSCH & LOMB (US) | 2012-03-14 | — | — | EP | disclosed |