Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 6/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8259379 | 1.00 | REN (0.34) | RENMCHR1CNR1CNR2ALDH1A1 | |
| SCHEMBL3465115 | 1.00 | REN (0.34) | RENMCHR1CNR1CNR2ALDH1A1 | |
| SCHEMBL8258770 | 0.95 | REN (0.35) | RENMCHR1ALDH1A1MAPTMEN1 | |
| SCHEMBL3465525 | 0.95 | REN (0.35) | RENMCHR1ALDH1A1MAPTMEN1 | |
| SCHEMBL2918953 | 0.95 | REN (0.37) | RENMCHR1ALDH1A1MAPTMEN1 | |
| SCHEMBL2916390 | 0.92 | REN (0.34) | RENMCHR1CNR1CNR2ALDH1A1 | |
| SCHEMBL3466476 | 0.91 | REN (0.35) | RENALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL4583132 | 0.91 | REN (0.35) | RENALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL8257866 | 0.91 | REN (0.35) | RENALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL3561065 | 0.90 | REN (0.36) | RENALDH1A1MAPTKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863803-B1 | SUBSTITUTED PIPERIDINES | NOVARTIS AG (CH) | 2010-09-01 | — | — | EP | disclosed |