Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 4/20 | 0.35 |
| ▸ | RORC | P51449 | 5/20 | 0.31 |
| ▸ | THRB | P10828 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3466476 | 1.00 | REN (0.35) | RENRORCTHRBALDH1A1CYP3A4 | |
| SCHEMBL8257866 | 1.00 | REN (0.35) | RENRORCTHRBALDH1A1CYP3A4 | |
| SCHEMBL2915124 | 0.95 | REN (0.38) | RENRORC | |
| SCHEMBL2917904 | 0.95 | REN (0.38) | RENRORC | |
| SCHEMBL2926428 | 0.95 | REN (0.33) | REN | |
| SCHEMBL2920516 | 0.94 | REN (0.36) | RENRORCTHRBALDH1A1CYP3A4 | |
| SCHEMBL2925320 | 0.94 | REN (0.36) | RENRORCTHRBALDH1A1CYP3A4 | |
| SCHEMBL3561065 | 0.94 | REN (0.36) | RENRORCTHRBALDH1A1CYP3A4 | |
| SCHEMBL14272005 | 0.94 | REN (0.36) | RENRORCTHRBALDH1A1CYP3A4 | |
| SCHEMBL2922512 | 0.93 | REN (0.33) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908762-A2 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |
| EP-1908761-A1 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |