Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30849354 | 1.00 | MAPKAPK2 (0.46) | MAPKAPK2HPGDGLAL3MBTL1CYP1A2 | |
| SCHEMBL29207165 | 0.89 | MAPT (0.49) | MAPKAPK2HPGDGLAL3MBTL1MEN1 | |
| SCHEMBL30849357 | 0.89 | MAPT (0.49) | MAPKAPK2HPGDGLAL3MBTL1MEN1 | |
| SCHEMBL29207121 | 0.88 | SMN1; SMN2 (0.55) | HPGDGLAL3MBTL1MEN1KMT2A | |
| SCHEMBL29207135 | 0.88 | MAPT (0.55) | MAPKAPK2HPGDL3MBTL1MEN1KMT2A | |
| SCHEMBL30849349 | 0.88 | MAPT (0.55) | MAPKAPK2HPGDL3MBTL1MEN1KMT2A | |
| SCHEMBL30849352 | 0.88 | SMN1; SMN2 (0.55) | HPGDGLAL3MBTL1MEN1KMT2A | |
| SCHEMBL29207123 | 0.88 | GPR174 (0.46) | HPGDGLAL3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL29207119 | 0.88 | KDM4E (0.51) | MAPKAPK2HPGDGLAL3MBTL1MEN1 | |
| SCHEMBL30849353 | 0.88 | KDM4E (0.51) | MAPKAPK2HPGDGLAL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117800916-A | Preparation and application of 1- [ (1H-indazol-7-yl) methyl ] -3-arylthiourea derivative | 沈阳药科大学 | 2024-04-02 | — | — | CN | disclosed |