Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30849349 | 1.00 | MAPT (0.55) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL29207165 | 0.89 | MAPT (0.49) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL30849357 | 0.89 | MAPT (0.49) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL30849356 | 0.88 | ALDH1A1 (0.58) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL29207113 | 0.88 | ALDH1A1 (0.58) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL29207123 | 0.88 | GPR174 (0.46) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL30849350 | 0.88 | GPR174 (0.46) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL29207119 | 0.88 | KDM4E (0.51) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL30849353 | 0.88 | KDM4E (0.51) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL29207126 | 0.88 | MAPKAPK2 (0.46) | MAPTMEN1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117800916-A | Preparation and application of 1- [ (1H-indazol-7-yl) methyl ] -3-arylthiourea derivative | 沈阳药科大学 | 2024-04-02 | — | — | CN | disclosed |