SCHEMBL29207409

SCHEMBL29207409

CCCCCOc1cccc(-c2ccccc2-c2ccccc2)c1

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.56
TSHR P16473 1/20 0.55
PTPN11 Q06124 3/20 0.53
PTPN1 P18031 2/20 0.51
SOAT1 P35610 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP19A1 P11511 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
HDAC8 Q9BY41 1/20 0.49
GPBAR1 Q8TDU6 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
PLA2G4B P0C869 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5057431 0.98 TSHR (0.58) LTA4HTSHRPTPN11PTPN1SOAT1
Formic Acid SCHEMBL28457373 0.92 PTPN11 (0.53) LTA4HTSHRPTPN11PTPN1HDAC8
SCHEMBL17905718 0.88 LTA4H (0.61) LTA4HTSHRCYP1A2CYP19A1CYP2C9
SCHEMBL9583558 0.87 TSHR (0.52) LTA4HTSHRPTPN11CYP1A2CYP19A1
SCHEMBL9229928 0.86 PTPN11 (0.74) TSHRPTPN11PLA2G4B
SCHEMBL3459345 0.86 TSHR (0.55) LTA4HTSHRPTPN11PTPN1CYP1A2
Hydrochloric Acid SCHEMBL9222118 0.85 PTPN11 (0.72) TSHRPTPN11PLA2G4B
SCHEMBL31550426 0.85 LTA4H (0.66) LTA4HTSHRPTPN11PTPN1CYP1A2
SCHEMBL17142884 0.84 TSHR (0.69) LTA4HTSHRPTPN11CYP1A2CYP19A1
SCHEMBL2151432 0.84 TSHR (0.69) LTA4HTSHRPTPN11CYP1A2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112300250-B Anidulafungin analogue and preparation method thereof 上海医药工业研究院 2024-03-19 CN disclosed