SCHEMBL3459345

SCHEMBL3459345

CCCCCCOc1cccc(-c2ccccc2[SiH3])c1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.55
PTPN11 Q06124 3/20 0.50
PLA2G4B P0C869 3/20 0.48
LTA4H P09960 1/20 0.47
SMPD1 P17405 3/20 0.47
CYP1A2 P05177 1/20 0.47
CYP19A1 P11511 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
PDK2 Q15119 1/20 0.45
PTPN1 P18031 1/20 0.45
GPBAR1 Q8TDU6 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
GGPS1 O95749 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5057431 0.88 TSHR (0.58) TSHRPTPN11PLA2G4BLTA4HSMPD1
SCHEMBL29207409 0.86 LTA4H (0.56) TSHRPTPN11PLA2G4BLTA4HCYP1A2
SCHEMBL2151432 0.84 TSHR (0.69) TSHRPTPN11PLA2G4BLTA4HSMPD1
SCHEMBL17142884 0.84 TSHR (0.69) TSHRPTPN11PLA2G4BLTA4HSMPD1
SCHEMBL17143201 0.84 TSHR (0.69) TSHRPTPN11PLA2G4BLTA4HSMPD1
SCHEMBL9583558 0.83 TSHR (0.52) TSHRPTPN11PLA2G4BLTA4HSMPD1
SCHEMBL17905718 0.81 LTA4H (0.61) TSHRLTA4HCYP1A2CYP19A1CYP2C9
Bromide SCHEMBL10655944 0.80 TSHR (0.59) TSHRPTPN11PLA2G4BLTA4HSMPD1
SCHEMBL9224698 0.80 TSHR (0.49) TSHRPTPN11PLA2G4BLTA4HSMPD1
SCHEMBL9682289 0.80 CNR1 (0.49) TSHRPTPN11PLA2G4BLTA4HSMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7667750-B2 Photoelectric-conversion-layer-stack-type color solid-state imaging device FUJIFILM CORPORATION (JP) 2010-02-23 US disclosed
US-7400023-B2 Photoelectric converting film stack type solid-state image pickup device and method of producing the same FUJIFILM CORPORATION (JP) 2008-07-15 US disclosed
US-20070279501-A1 PHOTOELECTRIC-CONVERSION-LAYER-STACK-TYPE COLOR SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2007-12-06 US disclosed
US-20050230775-A1 Photoelectric converting film stack type solid-state image pickup device and method of producing the same FUJI PHOTO FILM CO., LTD. 2005-10-20 US disclosed