Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | STS | P08842 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | CTSE | P14091 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13930884 | 0.83 | LMNA (0.59) | LMNAMAPTSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL27022355 | 0.82 | ALDH1A1 (0.71) | LMNAMAPTSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL28169019 | 0.79 | ALDH1A1 (0.62) | LMNAMAPTSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL24011150 | 0.79 | SMN1; SMN2 (0.64) | LMNAMAPTSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL29207994 | 0.79 | ALDH1A1 (0.62) | SMN1; SMN2ALDH1A1KMT2APKM | |
| SCHEMBL7381166 | 0.79 | ALDH1A1 (0.69) | LMNAMAPTSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL20015307 | 0.78 | ALDH1A1 (0.61) | LMNAMAPTSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL4155287 | 0.76 | ALDH1A1 (0.59) | LMNAMAPTSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL19123612 | 0.76 | ALDH1A1 (0.51) | LMNAMAPTSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL26668550 | 0.76 | KDM4E (0.56) | LMNAMAPTSMN1; SMN2TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964547-A | Urea compound and application thereof as Sigma2 and 5HT2A dual-target inhibitor | 瀚远医药有限公司 | 2024-05-03 | — | — | CN | disclosed |