Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29208796 | 0.84 | PPARG (0.42) | SMN1; SMN2HPGDRECQLMEN1KMT2A | |
| SCHEMBL29208797 | 0.83 | SMN1; SMN2 (0.40) | SMN1; SMN2HPGDRECQLMEN1KMT2A | |
| SCHEMBL26127561 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2HPGDRECQLMEN1KMT2A | |
| SCHEMBL9400930 | 0.75 | SMN1; SMN2 (0.71) | SMN1; SMN2HPGDMEN1KMT2APPARG | |
| SCHEMBL26120396 | 0.73 | SMN1; SMN2 (0.44) | SMN1; SMN2HPGDRECQLMEN1KMT2A | |
| SCHEMBL29168931 | 0.73 | PPARG (0.48) | SMN1; SMN2HPGDRECQLMEN1KMT2A | |
| SCHEMBL29208723 | 0.73 | SMN1; SMN2 (0.44) | SMN1; SMN2HPGDRECQLMEN1KMT2A | |
| SCHEMBL26123468 | 0.71 | GPR119 (0.48) | SMN1; SMN2HPGDRECQLMEN1KMT2A | |
| SCHEMBL26124908 | 0.71 | SMN1; SMN2 (0.46) | SMN1; SMN2HPGDRECQLMEN1KMT2A | |
| SCHEMBL31647906 | 0.70 | SMN1; SMN2 (0.46) | SMN1; SMN2HPGDRECQLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777099-A | PARP7 inhibitors and uses thereof | 诺沃斯达药业(上海)有限公司 | 2024-03-29 | — | — | CN | disclosed |