Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TIPARP | Q7Z3E1 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20565606 | 0.87 | RIPK1 (0.39) | SMN1; SMN2HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL26124908 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2HPGDMEN1KMT2AGPR119 | |
| SCHEMBL26123468 | 0.76 | GPR119 (0.48) | SMN1; SMN2HPGDMEN1KMT2AGPR119 | |
| SCHEMBL25075358 | 0.76 | LCAT (0.41) | GPR119KDM4ESLC6A9TIPARP | |
| SCHEMBL23296594 | 0.74 | TIPARP (0.39) | SMN1; SMN2HPGDMEN1KMT2AGPR119 | |
| SCHEMBL23296596 | 0.74 | TIPARP (0.39) | SMN1; SMN2HPGDMEN1KMT2AGPR119 | |
| SCHEMBL9400930 | 0.73 | SMN1; SMN2 (0.71) | SMN1; SMN2HPGDMEN1KMT2AGPR119 | |
| SCHEMBL25767140 | 0.73 | OPRK1 (0.46) | SMN1; SMN2HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL25075310 | 0.73 | CXCR3 (0.39) | GPR119TIPARP | |
| SCHEMBL29208724 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2HPGDMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777099-A | PARP7 inhibitors and uses thereof | 诺沃斯达药业(上海)有限公司 | 2024-03-29 | — | — | CN | disclosed |