SCHEMBL2920883

SCHEMBL2920883

O=C(c1ccccc1)c1cc[c]c(F)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.55
ATM Q13315 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
ALDH1A1 P00352 2/20 0.52
PBRM1 Q86U86 1/20 0.47
SRD5A2 P31213 1/20 0.45
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CNR1 P21554 1/20 0.42
CNR2 P34972 1/20 0.42
MAPT P10636 2/20 0.41
PTGS1 P23219 2/20 0.41
CXCR1 P25024 2/20 0.41
CXCR2 P25025 2/20 0.41
PTGS2 P35354 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL142939 0.80 TSHR (0.40) L3MBTL1ALDH1A1SRD5A2RAB9ACA1
SCHEMBL28988601 0.79 L3MBTL1 (0.57) L3MBTL1ATMTDP1ALDH1A1PBRM1
SCHEMBL1452138 0.79 L3MBTL1 (0.57) L3MBTL1ATMTDP1ALDH1A1PBRM1
SCHEMBL2922626 0.78 L3MBTL1 (0.55) L3MBTL1ATMTDP1ALDH1A1PBRM1
SCHEMBL3393204 0.78 L3MBTL1 (0.55) L3MBTL1ATMTDP1ALDH1A1PBRM1
SCHEMBL3894955 0.78 L3MBTL1 (0.55) L3MBTL1ATMTDP1ALDH1A1PBRM1
SCHEMBL9786573 0.76 L3MBTL1 (0.53) L3MBTL1ATMTDP1ALDH1A1PBRM1
SCHEMBL27568084 0.76 ELANE (0.53) L3MBTL1ATMTDP1ALDH1A1PBRM1
SCHEMBL425996 0.75 PARP1 (0.48) L3MBTL1TDP1ALDH1A1MEN1KMT2A
SCHEMBL4110333 0.74 L3MBTL1 (0.50) L3MBTL1ATMTDP1ALDH1A1PBRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8383862-B2 Salt compound, cationic polymerization initiator and cationically polymerizable composition ADEKA CORPORATION (JP) 2013-02-26 US disclosed
EP-2223948-B1 SALT COMPOUND, CATIONIC POLYMERIZATION INITIATOR AND CATIONICALLY POLYMERIZABLE COMPOSITION ADEKA CORP (JP) 2013-01-23 EP disclosed
US-20100267857-A1 SALT COMPOUND, CATIONIC POLYMERIZATION INITIATOR AND CATIONICALLY POLYMERIZABLE COMPOSITION ADEKA CORPORATION (JP) 2010-10-21 US disclosed
EP-2223948-A1 SALT COMPOUND, CATIONIC POLYMERIZATION INITIATOR AND CATIONICALLY POLYMERIZABLE COMPOSITION Adeka Corporation (JP) 2010-09-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267857-A1 SALT COMPOUND, CATIONIC POLYMERIZATION INITIATOR AND CATIONICALLY POLYMERIZABLE COMPOSITION RFC5, RER1, ARF5 L3MBTL1 4774/4885ATM 3121/4885TDP1 3143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.