Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GLS | O94925 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.43 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2711407 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1POLBGLSRAB9A | |
| SCHEMBL6031607 | 0.79 | MAPT (0.52) | SMN1; SMN2ALDH1A1RAB9ANPC1LMNA | |
| SCHEMBL6033285 | 0.77 | GABRP (0.49) | SMN1; SMN2ALDH1A1POLBGLSRAB9A | |
| Trifluoroacetic Acid SCHEMBL308773 | 0.74 | MAPT (0.49) | SMN1; SMN2ALDH1A1RAB9ANPC1LMNA | |
| Trifluoroacetic Acid SCHEMBL308772 | 0.74 | MAPT (0.49) | SMN1; SMN2ALDH1A1RAB9ANPC1LMNA | |
| SCHEMBL6032798 | 0.74 | MAPT (0.47) | SMN1; SMN2ALDH1A1RAB9ANPC1LMNA | |
| SCHEMBL308041 | 0.74 | MAPT (0.53) | SMN1; SMN2ALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL308040 | 0.74 | MAPT (0.53) | SMN1; SMN2ALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL307095 | 0.73 | ROCK2 (0.54) | — | |
| SCHEMBL307094 | 0.73 | ROCK2 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118026952-A | Pramipexole prodrug, long-acting preparation and application thereof | 天地恒一制药股份有限公司 | 2024-05-14 | — | — | CN | disclosed |