Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 8/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 6/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | HTR1F | P30939 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30881908 | 0.74 | PDK2 (0.41) | PDK2PDK4DRD2SLC6A4PDK1 | |
| SCHEMBL14416828 | 0.74 | HRH4 (0.42) | KDM4EHSD17B10MAPT | |
| SCHEMBL4699239 | 0.74 | HRH4 (0.44) | DDB1CRBNKDM4EHSD17B10L3MBTL1 | |
| SCHEMBL3364397 | 0.69 | MAPT (0.47) | KDM4EHSD17B10MAPT | |
| SCHEMBL29209760 | 0.68 | PDK2 (0.43) | PDK2PDK4PDK1ACHEHSD17B10 | |
| SCHEMBL30881643 | 0.68 | PDK2 (0.43) | PDK2PDK4PDK1ACHEHSD17B10 | |
| SCHEMBL30881751 | 0.67 | NR4A2 (0.54) | PDK2PDK4PDK1CRBNACHE | |
| SCHEMBL24507290 | 0.66 | PDK2 (0.38) | PDK2PDK4PDK1ACHEHSD17B10 | |
| SCHEMBL29304933 | 0.66 | MAT2A (0.34) | PDK2PDK4 | |
| SCHEMBL2914480 | 0.65 | MAPT (0.46) | ACHEKDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024099269-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, USE THEREOF | 华东师范大学 | 2024-05-16 | — | — | WO | disclosed |
| CN-118026880-A | Aryl amide compound, pharmaceutical composition containing same and application thereof | 华东师范大学 | 2024-05-14 | — | — | CN | disclosed |