Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 6/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29209690 | 0.74 | PDK2 (0.38) | PDK2PDK4DDB1CRBNDRD2 | |
| SCHEMBL16006573 | 0.74 | ALKBH5 (0.43) | DDB1CRBNGSK3BHSD17B10ALDH1A1 | |
| SCHEMBL16154737 | 0.73 | GSK3B (0.36) | DDB1CRBNGSK3BHSD17B10ALDH1A1 | |
| SCHEMBL20079002 | 0.73 | ELANE (0.36) | DDB1CRBNELANEGSK3BMEN1 | |
| SCHEMBL15995385 | 0.73 | DDB1 (0.38) | DDB1CRBNGSK3BHSD17B10ALDH1A1 | |
| SCHEMBL9181361 | 0.73 | SCN9A (0.42) | DDB1CRBNGSK3BHSD17B10ALDH1A1 | |
| SCHEMBL22886513 | 0.70 | GSK3B (0.36) | DDB1CRBNGSK3BDHFRHSD17B10 | |
| SCHEMBL25597602 | 0.70 | KEAP1 (0.42) | DDB1CRBNHSD17B10ALDH1A1HPGD | |
| SCHEMBL5085091 | 0.68 | PRMT5 (0.57) | PDK2PDK4DRD2SLC6A4HSD17B10 | |
| SCHEMBL31330879 | 0.67 | TDP1 (0.47) | ALDH1A1MAPK1L3MBTL1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024099269-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, USE THEREOF | 华东师范大学 | 2024-05-16 | — | — | WO | disclosed |
| CN-118026880-A | Aryl amide compound, pharmaceutical composition containing same and application thereof | 华东师范大学 | 2024-05-14 | — | — | CN | disclosed |