Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30881655 | 1.00 | HPGD (0.38) | HPGDALDH1A1MAPTHTTTSHR | |
| SCHEMBL18502962 | 0.84 | HPGD (0.38) | HPGDALDH1A1MAPTHTTTSHR | |
| SCHEMBL18508559 | 0.84 | HPGD (0.38) | HPGDALDH1A1MAPTHTTTSHR | |
| SCHEMBL20150803 | 0.82 | HPGD (0.37) | HPGDALDH1A1MAPTHTTTSHR | |
| SCHEMBL20148179 | 0.82 | HPGD (0.37) | HPGDALDH1A1MAPTHTTTSHR | |
| SCHEMBL18508600 | 0.79 | ALDH1A1 (0.38) | HPGDALDH1A1MAPTHTTTSHR | |
| SCHEMBL1816565 | 0.79 | HPGD (0.35) | HPGDALDH1A1MAPTHTTTSHR | |
| SCHEMBL1816566 | 0.79 | HPGD (0.35) | HPGDALDH1A1MAPTHTTTSHR | |
| SCHEMBL18502983 | 0.79 | ALDH1A1 (0.38) | HPGDALDH1A1MAPTHTTTSHR | |
| SCHEMBL20148177 | 0.77 | L3MBTL1 (0.39) | HPGDALDH1A1MAPTHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118026880-A | Aryl amide compound, pharmaceutical composition containing same and application thereof | 华东师范大学 | 2024-05-14 | — | — | CN | disclosed |