Formaldehyde

Formaldehyde

SCHEMBL29210889

C=O.COc1ncccc1Br

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.43
BTK Q06187 1/20 0.42
HKDC1 Q2TB90 1/20 0.41
PADI1 Q9ULC6 1/20 0.41
PADI3 Q9ULW8 1/20 0.41
PADI4 Q9UM07 1/20 0.41
PADI2 Q9Y2J8 1/20 0.41
ATG4B Q9Y4P1 1/20 0.41
HTR2A P28223 1/20 0.40
HTR2C P28335 1/20 0.40
ALDH1A1 P00352 1/20 0.38
NFE2L2 Q16236 2/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
SLC13A5 Q86YT5 1/20 0.36
PDE10A Q9Y233 1/20 0.36
DRD1 P21728 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
NSD2 O96028 1/20 0.36
CASP6 P55212 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30181916 0.94
SCHEMBL610170 0.94
SCHEMBL29133119 0.83 HTR2A (0.40) APLNRBTKHKDC1PADI1PADI3
SCHEMBL29535024 0.80
SCHEMBL3878940 0.76 PDE10A (0.43) ALDH1A1PDE10ADRD1TDP1NPC1
Formaldehyde SCHEMBL28298897 0.76 PLAU (0.43) HKDC1PADI1PADI3PADI4PADI2
SCHEMBL20406612 0.76 PDE10A (0.48) ALDH1A1PDE10ADRD1TDP1NPC1
SCHEMBL4008456 0.76 HTR1A (0.51) HTR2AHTR2CALDH1A1CA1CA2
SCHEMBL1842773 0.73 HPGD (0.53) ALDH1A1SLC13A5TDP1NPC1
SCHEMBL458403 0.73 TSHR (0.45) APLNRHTR2AHTR2CALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118043041-A LPAR1 antagonists and uses thereof 康蒂内乌姆医疗公司 2024-05-14 CN disclosed