SCHEMBL610170

SCHEMBL610170

COc1ncccc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30181916 1.00
Formaldehyde SCHEMBL29210889 0.94 APLNR (0.43)
SCHEMBL29535024 0.85
SCHEMBL29133119 0.84 HTR2A (0.40)
SCHEMBL3878940 0.81 PDE10A (0.43)
SCHEMBL4008456 0.81 HTR1A (0.51)
SCHEMBL20406612 0.81 PDE10A (0.48)
SCHEMBL1842773 0.78 HPGD (0.53)
SCHEMBL458403 0.78 TSHR (0.45)
SCHEMBL1845046 0.77 LRRK2 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 514 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022041617-A1 DIPHOSPHITE, PREPARATION METHOD THEREFOR AND USE THEREOF 中国海洋石油集团有限公司 2022-03-03 WO claimed
CN-112010906-B Bisphosphite and preparation method and application thereof 中国海洋石油集团有限公司 2021-09-28 CN claimed
CN-112010906-A Bisphosphite and preparation method and application thereof 中国海洋石油集团有限公司 2020-12-01 CN claimed
CN-104725301-A Preparation method of 1,2-dihydropyridin-2-one derivative BEIJING LABWORLD BIO MEDICINE TECHNOLOGY CO LTD 2015-06-24 CN claimed
CN-104649963-A Preparation technology of perampanel intermediate SUZHOU LAKESTAR PHARMATECH CO LTD 2015-05-27 CN claimed
CN-102491862-B Method for preparing biaryl compound in pure water UNIV DALIAN TECH 2014-06-25 CN claimed
CN-103588597-A Method for preparing biaryl compound in pure water UNIV DALIAN TECH 2014-02-19 CN claimed
CN-102083317-A Fungicidal compositions and methods for controlling plant diseases ISHIHARA SANGYO KAISHA 2011-06-01 CN claimed
CN-1874680-A bactericide composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA (JP) 2006-12-06 CN claimed
EP-4743453-A1 MODULATORS OF MITOCHONDRIAL DNA REPLICATION Pretzel Therapeutics, Inc. (US) 2026-05-20 EP disclosed
EP-3911640-B1 PCSK9 INHIBITORS FOR USE IN THERAPY, ESPECIALLY THE TREATMENT OF CARDIOVASCULAR DISEASE ASTRAZENECA AB (SE) 2026-05-13 EP disclosed
US-12606540-B2 Triazolone compound MEDSHINE DISCOVERY INC. (CN) 2026-04-21 US disclosed
US-12584120-B2 PCSK9 inhibitors and methods of use thereof ASTRAZENECA AB (SE) 2026-03-24 US disclosed
US-12552807-B2 PCSK9 inhibitors and methods of use thereof ASTRAZENECA AB (SE) 2026-02-17 US disclosed
US-5409930-A Inhibits abnoramal cell proliferation; dimethoxyquinoline/ dimethylquinoline/ quinolineoxide/ and quinoxaline derivatives RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1995-04-25 US disclosed
WO-1992020642-A1 BIS MONO-AND BICYCLIC ARYL AND HETEROARYL COMPOUNDS WHICH INHIBIT EGF AND/OR PDGF RECEPTOR TYROSINE KINASE RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) 1992-11-26 WO disclosed
US-4931452-A N-cyanomethyl-2-pyridinone insecticides THE DOW CHEMICAL COMPANY (US) 1990-06-05 US disclosed
CN-1034715-A N-cyanogen methyl-2-pyridinone insecticides DOW CHEMICAL CO (US) 1989-08-16 CN disclosed
WO-1989004301-A1 N-CYANOMETHYL-2-PYRIDINONE INSECTICIDES THE DOW CHEMICAL COMPANY (US) 1989-05-18 WO disclosed
EP-0316185-A2 N-cyanomethyl-2-pyridinone insecticides THE DOW CHEMICAL COMPANY (US) 1989-05-17 EP disclosed