Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2912971 | 0.85 | CYP1A2 (0.43) | HTTPOLBRAB9AMEN1KMT2A | |
| SCHEMBL7029119 | 0.81 | MEN1 (0.43) | HTTPOLBRAB9AMEN1LMNA | |
| SCHEMBL2921100 | 0.77 | PKM (0.39) | HTTPOLBRAB9AMEN1LMNA | |
| SCHEMBL2919368 | 0.77 | MAPT (0.42) | HTTPOLBRAB9AMEN1LMNA | |
| SCHEMBL2922182 | 0.75 | TYMS (0.35) | HTTPOLBRAB9AMEN1KMT2A | |
| SCHEMBL2919854 | 0.75 | CYP3A4 (0.46) | HTTPOLBMEN1LMNAKMT2A | |
| SCHEMBL12492530 | 0.71 | MEN1 (0.52) | HTTPOLBMEN1LMNAKMT2A | |
| SCHEMBL1465844 | 0.71 | HTT (0.40) | HTTPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL23213701 | 0.69 | ALDH1A1 (0.49) | HTTPOLBMEN1LMNAKMT2A | |
| SCHEMBL30407568 | 0.69 | ALDH1A1 (0.49) | HTTPOLBMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100311965-A1 | 2-AMINOQUINAZOLINE DERIVATIVE | CARNA BIOSCIENCES INC. (JP) | 2010-12-09 | — | — | US | disclosed |
| EP-2226315-A1 | 2-AMINOQUINAZOLINE DERIVATIVE | Carna Biosciences Inc. (JP) | 2010-09-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311965-A1 | 2-AMINOQUINAZOLINE DERIVATIVE | DSTYK, ABL1, EEF2K | HTT 4685/4885POLB 4054/4885RAB9A 1494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.