Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30743030 | 0.89 | ALDH1A1 (0.45) | ALDH1A1TSHRKMT2AMEN1L3MBTL1 | |
| SCHEMBL31083900 | 0.86 | ALDH1A1 (0.43) | ALDH1A1TSHRKMT2AMEN1L3MBTL1 | |
| SCHEMBL25765830 | 0.86 | ALDH1A1 (0.43) | ALDH1A1TSHRKMT2AMEN1L3MBTL1 | |
| SCHEMBL24894697 | 0.84 | ALDH1A1 (0.47) | ALDH1A1TSHRKMT2AMEN1L3MBTL1 | |
| SCHEMBL29580055 | 0.84 | ALDH1A1 (0.47) | ALDH1A1TSHRKMT2AMEN1L3MBTL1 | |
| SCHEMBL1446373 | 0.83 | ALDH1A1 (0.39) | ALDH1A1TSHRKMT2AMEN1L3MBTL1 | |
| SCHEMBL22969745 | 0.83 | ALDH1A1 (0.39) | ALDH1A1TSHRKMT2AMEN1L3MBTL1 | |
| SCHEMBL1446375 | 0.83 | ALDH1A1 (0.39) | ALDH1A1TSHRKMT2AMEN1L3MBTL1 | |
| SCHEMBL7869194 | 0.81 | ALDH1A1 (0.38) | ALDH1A1TSHRKMT2AMEN1L3MBTL1 | |
| SCHEMBL20942571 | 0.81 | ALDH1A1 (0.37) | ALDH1A1TSHRKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057740-B | Spiropyrimidinone derivatives, method for the production thereof, pharmaceutical compositions and use thereof | 上海赛默罗生物科技有限公司 | 2024-04-02 | — | — | CN | disclosed |