⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31270224 | 0.82 | — | — | |
| SCHEMBL31270434 | 0.76 | RXFP1 (0.35) | — | |
| SCHEMBL29212393 | 0.69 | EPAS1 (0.32) | — | |
| SCHEMBL25033220 | 0.68 | GPR119 (0.33) | — | |
| SCHEMBL31270355 | 0.68 | GPR119 (0.33) | — | |
| SCHEMBL29212336 | 0.67 | — | — | |
| SCHEMBL25033104 | 0.66 | CACNA1G (0.35) | — | |
| SCHEMBL31270065 | 0.66 | CACNA1G (0.35) | — | |
| SCHEMBL31726201 | 0.65 | CSNK1E (0.33) | — | |
| SCHEMBL31270262 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400591-A1 | COMPOUNDS TARGETING MUTANT OF P53 | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2024-12-05 | — | — | US | disclosed |
| CN-117813295-A | Compounds targeting p53 mutants | 北京加科思新药研发有限公司 | 2024-04-02 | — | — | CN | disclosed |