Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 6/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30184486 | 0.78 | GRM1 (0.32) | GRM1KCNH2 | |
| SCHEMBL30184629 | 0.77 | GRM1 (0.33) | GRM1KCNH2 | |
| SCHEMBL31270466 | 0.77 | GRM1 (0.31) | GRM1KCNH2 | |
| SCHEMBL29212491 | 0.64 | — | — | |
| SCHEMBL29212451 | 0.62 | — | — | |
| SCHEMBL29212406 | 0.62 | CA12 (0.42) | — | |
| SCHEMBL29212287 | 0.60 | MAOA (0.36) | — | |
| SCHEMBL29212402 | 0.57 | ALDH1A1 (0.35) | GRM1 | |
| SCHEMBL5509091 | 0.56 | PDPK1 (0.35) | — | |
| SCHEMBL20999929 | 0.56 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813295-A | Compounds targeting p53 mutants | 北京加科思新药研发有限公司 | 2024-04-02 | — | — | CN | disclosed |