Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 7/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 7/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29212287 | 0.78 | MAOA (0.36) | POLBMAOBMAPTGAA | |
| SCHEMBL30184453 | 0.75 | ALDH1A1 (0.33) | ALDH1A1POLBAPPPDE3BPDE3A | |
| SCHEMBL23143977 | 0.75 | LRRK2 (0.42) | ALDH1A1POLBMEN1KMT2AHTT | |
| SCHEMBL25033103 | 0.75 | ALDH1A1 (0.33) | ALDH1A1POLBAPPPDE3BPDE3A | |
| SCHEMBL29212402 | 0.75 | ALDH1A1 (0.35) | ALDH1A1POLBMEN1KMT2AHTT | |
| SCHEMBL10891365 | 0.74 | ALDH1A1 (0.62) | ALDH1A1POLBMEN1KMT2AHTT | |
| SCHEMBL29212361 | 0.74 | — | — | |
| SCHEMBL29212291 | 0.73 | CA12 (0.36) | ALDH1A1MAOB | |
| SCHEMBL30871297 | 0.73 | CYP1A2 (0.41) | ALDH1A1APPMEN1KMT2AHTT | |
| SCHEMBL29212272 | 0.70 | CLCN2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813295-A | Compounds targeting p53 mutants | 北京加科思新药研发有限公司 | 2024-04-02 | — | — | CN | disclosed |