SCHEMBL4004558

SCHEMBL4004558

[Li]C1C(CCC2=Cc3ccccc3C2[Li])=Cc2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9860029 0.91 HTR2A (0.32) HTR2A
SCHEMBL9859805 0.86 HTR2A (0.34) HTR2A
SCHEMBL29213166 0.85 BCHE (0.35) HTR2A
SCHEMBL5859366 0.83 CYP11B1 (0.33) HTR2A
SCHEMBL5090003 0.78
SCHEMBL31087274 0.78
SCHEMBL5604258 0.76 HTR2A (0.33) HTR2A
SCHEMBL217216 0.76 HTR2A (0.33) HTR2A
SCHEMBL6719841 0.76 DRD2 (0.39) HTR2A
SCHEMBL9860067 0.76 HTR2A (0.33) HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7619106-B2 Preparation of partially hydrogenated rac-ansa-metallocene complexes BASELL POLYOLEFINE GMBH (DE) 2009-11-17 US claimed
US-20080200708-A1 Preparation of Partially Hydrogenated Rac-Ansa-Metallocene Complexes BASELL POLYOLEFINE GMBH (DE) 2008-08-21 US claimed
EP-1554295-B1 PREPARATION OF PARTIALLY HYDROGENATED RAC-ANSA-METALLOCENE COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2008-07-02 EP claimed
EP-1554295-A1 PREPARATION OF PARTIALLY HYDROGENATED RAC-ANSA-METALLOCENE COMPLEXES Basell Polyolefine GmbH (DE) 2005-07-20 EP claimed
WO-2004037838-A1 PREPARATION OF PARTIALLY HYDROGENATED RAC-ANSA-METALLOCENE COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2004-05-06 WO claimed
JP-3152105-A None JP disclosed
US-7619106-B2 Preparation of partially hydrogenated rac-ansa-metallocene complexes BASELL POLYOLEFINE GMBH (DE) 2009-11-17 US disclosed
EP-1556417-B1 RACEMOSELECTIVE PREPARATION OF BRIDGED METALLOCENE COMPLEXES HAVING UNSUBSTITUTED OR 2-SUBSTITUTED INDENYL LIGANDS BASELL POLYOLEFINE GMBH (DE) 2009-06-10 EP disclosed
US-20080200708-A1 Preparation of Partially Hydrogenated Rac-Ansa-Metallocene Complexes BASELL POLYOLEFINE GMBH (DE) 2008-08-21 US disclosed
EP-1554295-B1 PREPARATION OF PARTIALLY HYDROGENATED RAC-ANSA-METALLOCENE COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2008-07-02 EP disclosed
US-7160949-B2 Olefin block copolymers, processes for producing the same and uses thereof MITSUI CHEMICALS, INC. (JP) 2007-01-09 US disclosed
EP-1275670-B1 OLEFIN BLOCK COPOLYMERS, PRODUCTION PROCESSES OF THE SAME AND USE THEREOF MITSUI CHEMICALS INC (JP) 2005-08-10 EP disclosed
US-20030055179-A1 Olefin block copolymers processes for producing the same and uses thereof MITSUI CHEMICALS, INC. (JP) 2003-03-20 US disclosed
EP-1275670-A1 OLEFIN BLOCK COPOLYMERS, PRODUCTION PROCESSES OF THE SAME AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2003-01-15 EP disclosed
EP-0452920-B1 Process for the preparation of an ethylene copolymer and an olefin polymer, and catalysts for olefin polymerization MITSUI CHEMICALS INC (JP) 2001-10-10 EP disclosed
US-5883205-A ETHYLENE POLYMERIZATION IN SUSPENSION OR VAPOR PHASE WITH CATALYST OF CYCLOPENTADIENE, TRANSITION METAL, ORGANOALUMINUM OXY COMPOUND MITSUI CHEMICALS, INC. (JP) 1999-03-16 US disclosed
US-5840815-A POLYMERIZING OLEFIN IN PRESENCE OF SOLID CATALYST FORMED FROM COMPOUND OF GROUP IVB METAL HAVING CYCLOPENTADIENE-BASED LIGANDS, ORGANOALUMINUM OXY-COMPOUND MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-11-24 US disclosed
EP-0462588-A2 Olefin block copolymer and method of producing same MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1991-12-27 EP disclosed
EP-0452920-A2 Process for the preparation of an ethylene copolymer and an olefin polymer, and catalysts for olefin polymerization MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-10-23 EP disclosed
JP-H03152105-A PRODUCTION OF POLYOLEFIN MITSUBISHI PETROCHEM CO LTD 1991-06-28 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080200708-A1 Preparation of Partially Hydrogenated Rac-Ansa-Metallocene Complexes HRAS, RAP1A, NBAS HTR2A 1313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.