Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 9/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7944975 | 0.90 | MEN1 (0.74) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7461518 | 0.79 | NPC1 (0.60) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL30833314 | 0.78 | MEN1 (0.82) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29181052 | 0.78 | MEN1 (0.82) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29477209 | 0.77 | DYRK1A (0.70) | MEN1KMT2AHTTSMN1; SMN2NPC1 | |
| SCHEMBL27173084 | 0.77 | DYRK1A (0.70) | MEN1KMT2AHTTSMN1; SMN2NPC1 | |
| SCHEMBL9893074 | 0.76 | DYRK1A (0.72) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7923452 | 0.76 | DYRK1A (0.68) | MEN1KMT2AHTTSMN1; SMN2NPC1 | |
| SCHEMBL11337093 | 0.75 | RAB9A (0.64) | MEN1KMT2ACYP1A2CYP2C19HTT | |
| SCHEMBL5928965 | 0.75 | DYRK1A (0.75) | MEN1KMT2ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117843579-A | Benzo heterocycle coupled catechol derivative and preparation method and application thereof | 暨南大学 | 2024-04-09 | — | — | CN | disclosed |