Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.70 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.70 |
| ▸ | CASP2 | P42575 | 1/20 | 0.68 |
| ▸ | CASP3 | P42574 | 9/20 | 0.65 |
| ▸ | SENP7 | Q9BQF6 | 9/20 | 0.65 |
| ▸ | SENP8 | Q96LD8 | 8/20 | 0.65 |
| ▸ | SENP6 | Q9GZR1 | 8/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | CLK1 | P49759 | 1/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.62 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27173084 | 1.00 | DYRK1A (0.70) | DYRK1AFSCN1CASP2CASP3SENP7 | |
| SCHEMBL7923452 | 0.87 | DYRK1A (0.68) | DYRK1AFSCN1CASP3SENP7SENP8 | |
| SCHEMBL9893074 | 0.87 | DYRK1A (0.72) | DYRK1AFSCN1CASP3SENP7SENP8 | |
| SCHEMBL5928965 | 0.86 | DYRK1A (0.75) | DYRK1AFSCN1CASP3SENP7SENP8 | |
| SCHEMBL4488390 | 0.85 | CASP2 (0.66) | DYRK1AFSCN1CASP2NPC1MAPT | |
| SCHEMBL30849479 | 0.84 | RAB9A (0.68) | DYRK1ACASP2NPC1MAPTMEN1 | |
| SCHEMBL17251987 | 0.84 | PDPK1 (0.68) | DYRK1ACASP2NPC1MAPTMEN1 | |
| SCHEMBL29477216 | 0.84 | RAB9A (0.72) | DYRK1ACASP2NPC1MAPTMEN1 | |
| SCHEMBL27173184 | 0.84 | RAB9A (0.68) | DYRK1ACASP2NPC1MAPTMEN1 | |
| SCHEMBL11920138 | 0.84 | RAB9A (0.72) | DYRK1ACASP2NPC1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024177606-A1 | QUINAZOLINONE DERIVATIVE COMPOUNDS SHOWING ANTI-CANCER ACTIVITY AND THE SYNTHESIS METHODS OF THESE COMPOUNDS | BILECIK SEYH EDEBALI UNIVERSITESI (TR) | 2024-08-29 | — | — | WO | claimed |
| EP-3959200-A1 | NEW TRIAZOLE AND TRIAZOLOTHIADIAZINE DERIVATIVES EXERTING CYTOTOXIC AND APOPTOTIC EFFECTS ON A549 CELLS THROUGH AKT INHIBITION | Anadolu Universitesi (TR) | 2022-03-02 | — | — | EP | claimed |
| CN-119954794-A | Flavonol derivative containing benzothiazole, and preparation method and application thereof | 贵州大学 | 2025-05-09 | — | — | CN | disclosed |
| WO-2024177606-A1 | QUINAZOLINONE DERIVATIVE COMPOUNDS SHOWING ANTI-CANCER ACTIVITY AND THE SYNTHESIS METHODS OF THESE COMPOUNDS | BILECIK SEYH EDEBALI UNIVERSITESI (TR) | 2024-08-29 | — | — | WO | disclosed |