SCHEMBL29213655

SCHEMBL29213655

Cc1ccc(N)c(N)c1N.O=C(Cl)Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD44 P16070 1/20 0.46
TDP1 Q9NUW8 4/20 0.43
MAPT P10636 2/20 0.43
POLB P06746 1/20 0.41
CYP3A4 P08684 6/20 0.38
TSHR P16473 4/20 0.36
ALDH1A1 P00352 5/20 0.36
CASP1 P29466 2/20 0.36
NPC1 O15118 1/20 0.34
MAPK1 P28482 1/20 0.34
CASP3 P42574 1/20 0.34
RAB9A P51151 1/20 0.34
HBB P68871 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
THRB P10828 1/20 0.34
KDM4E B2RXH2 2/20 0.33
NOS3 P29474 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL29210072 0.88 CD44 (0.44) CD44TDP1MAPTPOLBCYP3A4
SCHEMBL30565815 0.87 CD44 (0.57) CD44TDP1MAPTPOLBCYP3A4
SCHEMBL2056779 0.87 CD44 (0.57) CD44TDP1MAPTPOLBCYP3A4
Hydrochloric Acid SCHEMBL3725463 0.85 CD44 (0.55) CD44TDP1MAPTPOLBCYP3A4
Hydrochloric Acid SCHEMBL28212724 0.85 CD44 (0.55) CD44TDP1MAPTPOLBCYP3A4
SCHEMBL11396178 0.77 CD44 (0.43) CD44TDP1MAPTPOLBCYP3A4
Methyl Alcohol SCHEMBL7119741 0.76 POLB (0.55) CD44TDP1MAPTPOLBCYP3A4
SCHEMBL409314 0.76 POLB (0.61) CD44TDP1MAPTPOLBCYP3A4
SCHEMBL7597578 0.73 TDP1 (0.41) CD44TDP1MAPTPOLBCYP3A4
Carbamic Acid SCHEMBL8735463 0.73 TDP1 (0.41) CD44TDP1MAPTPOLBCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117820171-A Process method for synthesizing toluene triisocyanate by using triamino toluene phosgene 中国融通资源开发集团有限公司 2024-04-05 CN claimed