Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CD44 | P16070 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34364 | 0.86 | POLB (0.48) | TDP1MAPTPOLBCD44KDM4E | |
| SCHEMBL29366969 | 0.86 | POLB (0.48) | TDP1MAPTPOLBCD44KDM4E | |
| Hydrochloric Acid SCHEMBL5183951 | 0.84 | POLB (0.46) | TDP1MAPTPOLBCD44KDM4E | |
| Methane SCHEMBL701905 | 0.84 | POLB (0.46) | TDP1MAPTPOLBCD44KDM4E | |
| Hydrochloric Acid SCHEMBL10761313 | 0.84 | POLB (0.46) | TDP1MAPTPOLBCD44KDM4E | |
| Phthalic Acid SCHEMBL9869587 | 0.83 | ALDH1A1 (0.50) | TDP1POLBKDM4EKMT2AMEN1 | |
| Adipic Acid SCHEMBL9058463 | 0.83 | TSHR (0.42) | TDP1MAPTKMT2AMEN1TSHR | |
| Sulfuric Acid SCHEMBL30338570 | 0.83 | ALDH1A1 (0.39) | TDP1MAPTPOLBCD44KDM4E | |
| SCHEMBL29087964 | 0.79 | CD44 (0.42) | TDP1MAPTPOLBCD44KDM4E | |
| SCHEMBL29087953 | 0.79 | POLB (0.42) | TDP1MAPTPOLBCD44KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641361-B1 | FUSING MEMBER CONTAINING METAL OXIDE FREE FLUOROELASTOMER COMPOSITIONS | AMES RUBBER CORP (US) | 1998-02-18 | — | — | EP | disclosed |