Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 16/20 | 0.57 |
| ▸ | BRD9 | Q9H8M2 | 5/20 | 0.57 |
| ▸ | BRD4 | O60885 | 4/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.57 |
| ▸ | BRD1 | O95696 | 9/20 | 0.38 |
| ▸ | BRPF3 | Q9ULD4 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30873747 | 1.00 | BRPF1 (0.57) | BRPF1BRD9BRD4CA12CA9 | |
| SCHEMBL29213971 | 0.86 | BRPF1 (0.62) | BRPF1BRD9BRD4CA12CA9 | |
| SCHEMBL30873739 | 0.85 | BRPF1 (0.46) | BRPF1BRD9BRD4CA12CA9 | |
| SCHEMBL1119899 | 0.78 | BRPF1 (0.59) | BRPF1BRD9BRD4CA12CA9 | |
| SCHEMBL31743117 | 0.76 | BRPF1 (0.57) | BRPF1BRD9BRD4CA12CA9 | |
| SCHEMBL1948671 | 0.76 | BRPF1 (0.57) | BRPF1BRD9BRD4CA12CA9 | |
| SCHEMBL19231303 | 0.76 | BRPF1 (0.57) | BRPF1BRD9BRD4CA12CA9 | |
| SCHEMBL30538035 | 0.76 | BRPF1 (0.57) | BRPF1BRD9BRD4CA12CA9 | |
| SCHEMBL16932310 | 0.76 | BRPF1 (0.57) | BRPF1BRD9BRD4CA12CA9 | |
| SCHEMBL11743970 | 0.76 | BRPF1 (0.76) | BRPF1BRD9BRD4CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117551057-A | Benzo ring derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2024-02-13 | — | — | CN | disclosed |