SCHEMBL30538035

SCHEMBL30538035

Cn1c(=O)ccc2ccc(Br)cc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRPF1 P55201 9/20 0.57
BRD4 O60885 4/20 0.57
BRD9 Q9H8M2 3/20 0.57
CA12 O43570 1/20 0.57
CA9 Q16790 1/20 0.57
KAT2B Q92831 1/20 0.57
MCL1 Q07820 1/20 0.42
CDC7 O00311 1/20 0.41
CDK2 P24941 1/20 0.41
MAP3K14 Q99558 1/20 0.41
BRD1 O95696 3/20 0.38
BRPF3 Q9ULD4 2/20 0.38
HSD17B10 Q99714 1/20 0.38
KMO O15229 1/20 0.37
HTR7 P34969 1/20 0.37
MEN1 O00255 2/20 0.36
MAPT P10636 2/20 0.36
RAB9A P51151 2/20 0.36
KMT2A Q03164 2/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16932310 1.00 BRPF1 (0.57) BRPF1BRD4BRD9CA12CA9
Acetic Acid SCHEMBL9157141 0.91 BRPF1 (0.49) BRPF1BRD4BRD9CA12CA9
SCHEMBL2172818 0.86 BRPF1 (0.62) BRPF1BRD4BRD9CA12CA9
SCHEMBL1119899 0.78 BRPF1 (0.59) BRPF1BRD4BRD9CA12CA9
SCHEMBL19231303 0.76 BRPF1 (0.57) BRPF1BRD4BRD9CA12CA9
SCHEMBL31743117 0.76 BRPF1 (0.57) BRPF1BRD4BRD9CA12CA9
SCHEMBL1948671 0.76 BRPF1 (0.57) BRPF1BRD4BRD9CA12CA9
SCHEMBL30873747 0.76 BRPF1 (0.57) BRPF1BRD4BRD9CA12CA9
SCHEMBL29213984 0.76 BRPF1 (0.57) BRPF1BRD4BRD9CA12CA9
SCHEMBL11743970 0.76 BRPF1 (0.76) BRPF1BRD4BRD9CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025090514-A1 COVALENT SARM1 INHIBITORS NURA BIO, INC. (US) 2025-05-01 WO disclosed
CN-113645971-B Compounds and uses thereof 福宏治疗公司 2024-10-18 CN disclosed
CN-117551057-A Benzo ring derivative and preparation method and application thereof 浙江海正药业股份有限公司 2024-02-13 CN disclosed
CN-110483492-B Dipeptidyl peptidase I inhibitors 阿斯利康(瑞典)有限公司 2023-07-21 CN disclosed