Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.59 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.52 |
| ▸ | RELA | Q04206 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30861772 | 1.00 | APP (0.59) | APPBCHEALOX5ALOX15ACHE | |
| SCHEMBL18838214 | 0.89 | BCHE (0.55) | APPBCHEALOX5ALOX15ACHE | |
| SCHEMBL29214175 | 0.85 | MAOB (0.62) | APPALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL30861756 | 0.85 | MAOB (0.62) | APPALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL5204810 | 0.84 | MAOB (0.56) | APPALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL29873198 | 0.83 | APP (0.82) | APPALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL14833013 | 0.83 | APP (0.82) | APPALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL18838112 | 0.82 | APP (0.50) | APPBCHEALOX5ALOX15ACHE | |
| SCHEMBL30861750 | 0.81 | PTGES (0.50) | APPALDH1A1KDM4ELMNAMAOB | |
| SCHEMBL29214171 | 0.81 | PTGES (0.50) | APPALDH1A1KDM4ELMNAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063444-A | Azetidinamide derivatives and uses thereof | 广东东阳光药业股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-118063445-A | Pyrrolidine amide derivatives and use thereof | 广东东阳光药业股份有限公司 | 2024-05-24 | — | — | CN | disclosed |