Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 4/20 | 0.49 |
| ▸ | GABRD | O14764 | 4/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.49 |
| ▸ | GABRE | P78334 | 4/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.49 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.49 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.49 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30861750 | 1.00 | PTGES (0.50) | PTGESGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL5204810 | 0.84 | MAOB (0.56) | PTGESCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6239571 | 0.84 | MAOB (0.58) | PTGESGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL28896611 | 0.84 | GABRP (0.52) | PTGESGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29979155 | 0.84 | GABRP (0.52) | PTGESGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29214189 | 0.81 | APP (0.59) | PTGESGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL30861772 | 0.81 | APP (0.59) | PTGESGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL18003136 | 0.81 | GABRP (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27546448 | 0.81 | PTGES (0.47) | PTGESCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL18838193 | 0.79 | MAOB (0.46) | PTGESCHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063444-A | Azetidinamide derivatives and uses thereof | 广东东阳光药业股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-118063445-A | Pyrrolidine amide derivatives and use thereof | 广东东阳光药业股份有限公司 | 2024-05-24 | — | — | CN | disclosed |