Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.37 |
| ▸ | TUBB | P07437 | 3/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30311415 | 1.00 | KDM4E (0.39) | KDM4EHSD17B10ALOX15TSHRPTGS2 | |
| SCHEMBL30311578 | 0.86 | TUBB4A (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29215293 | 0.86 | TUBB4A (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6139350 | 0.85 | SMN1; SMN2 (0.40) | KDM4EGAASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL30311455 | 0.82 | TUBB4A (0.40) | KDM4EHSD17B10ALOX15TSHRTUBB4A | |
| SCHEMBL30311331 | 0.82 | TUBB4A (0.40) | KDM4ETSHRTP53TUBB4ATUBB | |
| SCHEMBL30311606 | 0.81 | ABCB1 (0.38) | PTGS2GAATP53TUBB4ATUBB | |
| SCHEMBL29215288 | 0.81 | PDE7A (0.40) | KDM4ETP53TUBB4ATUBBTUBA3C | |
| SCHEMBL30311488 | 0.80 | TSHR (0.46) | HSD17B10TSHRPDE4DSMN1; SMN2ALDH1A1 | |
| SCHEMBL29215297 | 0.80 | TSHR (0.46) | HSD17B10TSHRPDE4DSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076610-A | Macrocyclic compounds with ENT1 inhibitory activity | ITEOS比利时公司 | 2024-05-24 | — | — | CN | disclosed |