Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29999195 | 1.00 | PTPN1 (0.45) | PTPN1MGAMGAASIACHE | |
| SCHEMBL29999634 | 0.83 | KDM4E (0.49) | PTPN1MGAMGAASIACHE | |
| SCHEMBL9633675 | 0.72 | HIF1A (0.52) | PTPN1MGAMGAASIACHE | |
| SCHEMBL23746417 | 0.72 | HIF1A (0.52) | PTPN1MGAMGAASIACHE | |
| SCHEMBL10431871 | 0.71 | HIF1A (0.49) | PTPN1MGAMGAASIACHE | |
| SCHEMBL9634323 | 0.70 | HIF1A (0.49) | PTPN1MGAMGAASIACHE | |
| SCHEMBL8616456 | 0.69 | KDM4E (0.48) | PTPN1MGAMGAASIACHE | |
| SCHEMBL9634302 | 0.69 | HIF1A (0.52) | PTPN1MGAMGAASIACHE | |
| SCHEMBL3310654 | 0.68 | MGAM (0.47) | PTPN1MGAMGAASIACHE | |
| SCHEMBL8370012 | 0.68 | MGAM (0.47) | PTPN1MGAMGAASIACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794534-A | Compositions for modulating cortisol homeostasis and improving sleep quality and methods of use and preparation thereof | 尤尼根公司 | 2024-03-29 | — | — | CN | disclosed |