Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 7/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565737 | 0.85 | KDM1A (0.55) | KDM1AMAOAMAOBMAPTMAPK1 | |
| SCHEMBL28668399 | 0.83 | KDM1A (0.48) | KDM1AMAOAMAOBPTPN1MAPT | |
| SCHEMBL14882717 | 0.83 | KDM1A (0.60) | KDM1AMAOAMAOBMAPTMAPK1 | |
| SCHEMBL5020031 | 0.81 | KDM1A (0.54) | KDM1AMAOAMAOBPTPN1MAPT | |
| SCHEMBL28649266 | 0.80 | KDM1A (0.44) | KDM1AMAOAMAOBPTPN1MAPT | |
| SCHEMBL26942220 | 0.79 | LIPE (0.53) | KDM1AMAOAMAOBHTR1ASLC6A2 | |
| SCHEMBL26942219 | 0.77 | KDM1A (0.61) | KDM1AMAOAMAOBMAPTMAPK1 | |
| SCHEMBL18133317 | 0.77 | MAPT (0.55) | KDM1APTPN1MAPTMAPK1TDP1 | |
| SCHEMBL25430153 | 0.77 | KDM1A (0.48) | KDM1AMAOAMAOBHTR1ASLC6A2 | |
| SCHEMBL22701125 | 0.76 | NQO1 (0.36) | KDM1AMAPTTDP1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865773-A | Preparation method of difluoromethyl aromatic compound based on palladium-catalyzed decarbonylation coupling | 大连理工大学 | 2024-04-12 | — | — | CN | disclosed |