Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 7/20 | 0.55 |
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14882717 | 0.90 | KDM1A (0.60) | KDM1AMAOAMAOBSLC6A2SLC6A3 | |
| SCHEMBL29216487 | 0.85 | KDM1A (0.50) | KDM1AMAOAMAOBSLC6A2SLC6A3 | |
| SCHEMBL25430153 | 0.83 | KDM1A (0.48) | KDM1AMAOAMAOBSLC6A2SLC6A3 | |
| SCHEMBL21647646 | 0.81 | KDM1A (0.43) | KDM1AMAOAMAOBSLC6A2SLC6A3 | |
| SCHEMBL31266006 | 0.81 | LIPE (0.53) | KDM1AMAOAMAOBSLC6A2SLC6A3 | |
| SCHEMBL16033831 | 0.81 | KDM1A (0.47) | KDM1AMAOAMAOBSLC6A2SLC6A3 | |
| SCHEMBL3176483 | 0.81 | KDM1A (0.50) | KDM1AMAOAMAOBSLC6A2SLC6A3 | |
| SCHEMBL1766179 | 0.81 | MAPT (0.56) | KDM1AMAOAMAOBSLC6A2SLC6A3 | |
| SCHEMBL31266173 | 0.81 | KDM1A (0.53) | KDM1AMAOAMAOBSLC6A2SLC6A3 | |
| SCHEMBL25359554 | 0.81 | KDM1A (0.49) | KDM1AMAOAMAOBSLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849959-A | Derivatives of 2, 3, 6-trifluorophenols and a process for their preparation | CLARIANT GMBH (DE) | 1998-12-15 | — | — | US | disclosed |