SCHEMBL292165

SCHEMBL292165

CCC1CC[N]CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1547421 0.89
SCHEMBL11354632 0.82 NOS3 (0.37)
SCHEMBL1277021 0.82
SCHEMBL771485 0.77
SCHEMBL32667642 0.75 ALDH1A1 (0.37)
SCHEMBL43433 0.75
SCHEMBL2150283 0.75 ALDH1A1 (0.37)
SCHEMBL2222242 0.75 ALDH1A1 (0.37)
SCHEMBL3962258 0.73 CYP1A2 (0.58)
Hydrogen Sulfide SCHEMBL5675254 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 354 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114315689-B Disulfanylphthalimide compound, preparation method and application thereof 四川大学 2023-04-07 CN claimed
US-20230027716-A1 NOVEL PYRIDINYLTRIAZINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING, AMELIORATING, OR TREATING CANCER COMPRISING SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2023-01-26 US claimed
CN-114315689-A Disulfanylphthalimide compound, preparation method and application thereof 四川大学 2022-04-12 CN claimed
WO-2021080346-A1 NOVEL PYRIDINYLTRIAZINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING, AMELIORATING, OR TREATING CANCER COMPRISING SAME 한국과학기술연구원 2021-04-29 WO claimed
US-9586936-B2 Heteroarylamine derivatives as protein kinase inhibitors KOREA INSTITITUE OF SCIENCE AND TECHNOLOGY (KR) 2017-03-07 US claimed
US-20160145240-A1 HETEROARYLAMINE DERIVATIVES AS PROTEIN KINASE INHIBITORS KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2016-05-26 US claimed
US-9150545-B2 Carboxamide compounds and their use as calpain inhibitors V AbbVie Deutschland GmbH & Co. KG (DE) 2015-10-06 US claimed
US-20150065477-A1 CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS V AbbVie Deutschland GmbH & Co. KG (DE) 2015-03-05 US claimed
EP-2834230-A1 CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS V AbbVie Deutschland GmbH & Co KG (DE) 2015-02-11 EP claimed
EP-2831061-A1 TRIAZOLE DERIVATIVES AS HSP90 INHIBITORS Synta Pharmaceuticals Corp. (US) 2015-02-04 EP claimed
WO-2003070727-A1 THIAZOLYL UREA COMPOUNDS FOR THE TREATMENT OF CANCER AMGEN INC. (US) 2003-08-28 WO claimed
US-20020193405-A1 Thiazolyl urea compounds and methods of uses AMGEN INC. 2002-12-19 US claimed
US-4925849-A DIURETICS, HYPOTENSIVE AGENTS, CARIOTONIC AGENTS AND ANTIEDEMIC AGENTS FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1990-05-15 US claimed
EP-0299209-A2 Pyrazolopyridine compound and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-01-18 EP claimed
US-4599419-A ANTICOAGULANTS MITSUBISHI CHEMICAL INDUSTRIES, INC. (JP) 1986-07-08 US claimed
US-4481365-A POSTEMERGENCE BAYER AKTIENGESELLSCHAFT (DE) 1984-11-06 US claimed
US-4069323-A INHIBITION AND SUPPRESSION OF THROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1978-01-17 US claimed
US-4066758-A ANTITHROMBOTIC MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1978-01-03 US claimed
US-4062963-A N2 -naphthalenesulfonyl-L-arginine derivatives, and the pharmaceutically acceptable acid addition salts thereof MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1977-12-13 US claimed
US-4049645-A ANTITHROMBOTIC AGENTS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1977-09-20 US claimed