Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 3/20 | 0.46 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 5/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29217145 | 0.84 | STAT6 (0.41) | KDM4ESIRT5 | |
| SCHEMBL22866255 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNATP53NPSR1 | |
| SCHEMBL29217168 | 0.80 | MAPT (0.57) | ALDH1A1KDM4ETP53NPSR1MEN1 | |
| SCHEMBL2523948 | 0.79 | SYK (0.53) | ALDH1A1KDM4ELMNATP53NPSR1 | |
| SCHEMBL34462345 | 0.79 | NPSR1 (0.65) | ALDH1A1KDM4ELMNATP53NPSR1 | |
| SCHEMBL11582962 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KDM4ELMNATP53NPSR1 | |
| SCHEMBL4174181 | 0.78 | HTT (0.54) | ALDH1A1KDM4ELMNATP53NPSR1 | |
| SCHEMBL22401212 | 0.78 | MAPT (0.50) | ALDH1A1KDM4ELMNATP53NPSR1 | |
| SCHEMBL28684686 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KDM4ELMNATP53NPSR1 | |
| SCHEMBL22401294 | 0.77 | MAPT (0.49) | ALDH1A1KDM4ELMNATP53NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084892-A | Compounds useful as HPK1 inhibitors | 深圳福沃药业有限公司 | 2024-05-28 | — | — | CN | disclosed |