Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | PPP1CA | P62136 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.53 |
| ▸ | SIRT5 | Q9NXA8 | 4/20 | 0.49 |
| ▸ | SYK | P43405 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4188524 | 0.85 | CSNK2A2 (0.51) | LMNAKDM4EMEN1KMT2AADORA1 | |
| SCHEMBL22261345 | 0.84 | RPS6KB1 (0.54) | KDM4EMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL4178767 | 0.84 | CSNK2A2 (0.50) | LMNAKDM4EMEN1KMT2AADORA1 | |
| SCHEMBL29622807 | 0.84 | RPS6KB1 (0.54) | KDM4EMEN1KMT2AMAPT | |
| SCHEMBL1600523 | 0.83 | ADORA1 (0.53) | HTTALDH1A1NPSR1MAPK1LMNA | |
| SCHEMBL22866255 | 0.79 | ALDH1A1 (0.55) | HTTALDH1A1NPSR1MAPK1LMNA | |
| SCHEMBL34462345 | 0.79 | NPSR1 (0.65) | HTTALDH1A1NPSR1MAPK1LMNA | |
| SCHEMBL29217221 | 0.78 | ALDH1A1 (0.50) | HTTALDH1A1NPSR1MAPK1LMNA | |
| SCHEMBL15358450 | 0.78 | ADORA1 (0.51) | HTTALDH1A1NPSR1MAPK1LMNA | |
| SCHEMBL31141599 | 0.77 | HDAC3 (0.50) | NPSR1MEN1KMT2AADORA1SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090198057-A1 | Certain Chemical Entities, Compositions, and Methods | CYTOKINETICS, INCORPORATED | 2009-08-06 | — | — | US | disclosed |
| US-20090198057-A1 | Certain Chemical Entities, Compositions, and Methods | CYTOKINETICS, INCORPORATED | 2009-08-06 | — | — | US | disclosed |
| US-20090198057-A1 | Certain Chemical Entities, Compositions, and Methods | CYTOKINETICS, INCORPORATED | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090198057-A1 | Certain Chemical Entities, Compositions, and Methods | MYLK, MYH2, MYH10 | HTT 1845/4885ALDH1A1 1710/4885NPSR1 3598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.