Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4633729 | 0.80 | CYP2C19 (0.40) | MAPT | |
| SCHEMBL4633732 | 0.80 | CYP2C19 (0.40) | MAPT | |
| SCHEMBL27347522 | 0.80 | SLC6A2 (0.37) | CHRNA7STAT3ACHETDP1MAPT | |
| SCHEMBL10178994 | 0.77 | RIPK1 (0.39) | CHRNA7STAT3ACHETDP1MAPT | |
| SCHEMBL29217242 | 0.74 | PDE2A (0.39) | MAPTKMT2A | |
| P-Cymene SCHEMBL23798852 | 0.74 | ACHE (0.41) | CHRNA7STAT3ACHETDP1MAPT | |
| P-Cymene SCHEMBL23798851 | 0.72 | ACHE (0.40) | CHRNA7STAT3ACHETDP1MAPT | |
| SCHEMBL2745379 | 0.72 | RIPK1 (0.38) | CHRNA7STAT3ACHETDP1MAPT | |
| P-Cymene SCHEMBL28540406 | 0.69 | TSHR (0.46) | CHRNA7STAT3ACHEMAPTGAA | |
| SCHEMBL6400989 | 0.69 | CYP1A2 (0.39) | CHRNA7ACHETDP1MAPTALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084726-A | 1-Cyano-2-hydroxy-5-fluoro compound and preparation method thereof | 南京工业大学 | 2024-05-28 | — | — | CN | claimed |
| CN-118084726-A | 1-Cyano-2-hydroxy-5-fluoro compound and preparation method thereof | 南京工业大学 | 2024-05-28 | — | — | CN | disclosed |