Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1156727 | 0.82 | KMT2A (0.49) | KMT2AMEN1NPC1KDM4EALDH1A1 | |
| SCHEMBL1156084 | 0.77 | KMT2A (0.47) | KMT2AMEN1NPC1KDM4EALDH1A1 | |
| SCHEMBL3022185 | 0.76 | L3MBTL1 (0.45) | KMT2AMEN1NPC1KDM4EALDH1A1 | |
| SCHEMBL22473322 | 0.76 | KMT2A (0.47) | KMT2AMEN1NPC1KDM4EALDH1A1 | |
| SCHEMBL9838478 | 0.75 | NPC1 (0.52) | KMT2AMEN1NPC1KDM4EALDH1A1 | |
| SCHEMBL27491531 | 0.74 | HTR7 (0.54) | KMT2AMEN1NPC1KDM4EALDH1A1 | |
| SCHEMBL30676250 | 0.73 | MAPT (0.44) | KMT2AMEN1NPC1KDM4EALDH1A1 | |
| SCHEMBL30273389 | 0.73 | MAPT (0.44) | KMT2AMEN1NPC1KDM4EALDH1A1 | |
| SCHEMBL23456916 | 0.72 | KMT2A (0.44) | KMT2AMEN1NPC1KDM4EALDH1A1 | |
| SCHEMBL22473323 | 0.72 | KMT2A (0.44) | KMT2AMEN1NPC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113453760-B | APOL1 inhibitors and methods of use thereof | 弗特克斯药品有限公司 | 2024-05-24 | — | — | CN | disclosed |