Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.47 |
| ▸ | CTSS | P25774 | 4/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18987924 | 1.00 | CTSK (0.47) | CTSKCTSSCTSLCTSBCA1 | |
| Hydrochloric Acid SCHEMBL26645724 | 0.90 | CTSK (0.47) | CTSKCTSSCTSLCTSBCA1 | |
| Hydrochloric Acid SCHEMBL26645727 | 0.90 | CTSK (0.47) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL55833 | 0.87 | CTSL (0.60) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL55832 | 0.87 | CTSL (0.60) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL56907 | 0.87 | CTSL (0.60) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL23282458 | 0.86 | CTSK (0.46) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL22118348 | 0.85 | CTSK (0.51) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL18987919 | 0.85 | CTSK (0.51) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL26045045 | 0.85 | CTSK (0.48) | CTSKCTSSCTSLCTSBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113453760-B | APOL1 inhibitors and methods of use thereof | 弗特克斯药品有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-113453760-A | APOL1 inhibitors and methods of use thereof | 弗特克斯药品有限公司 | 2021-09-28 | — | — | CN | disclosed |